| Ecosystem | Type | Status | Ref. |
|---|---|---|---|
| Cape Fear River | River (basin) | native | 86798 |
| Chowan River | River (basin) | native | 86798 |
| James River | River (basin) | native | 86798 |
| Nearctic | Zoogeographic realm | endemic | 5723 |
| New River | River (basin) | native | 86798 |
| Roanoke River | River (basin) | native | 86798 |