n = 17
| Scientific Name | Author | Valid Name | Family | English Name |
|---|---|---|---|---|
| Profundulus adani | Dominguez-Cisneros, Velázquez-Velázquez, McMahan & Matamoros, 2021 | Genus Species | New species | |
| Profundulus balsanus | Ahl, 1935 | Profundulus punctatus | Profundulidae | Oaxaca killifish |
| Profundulus candalarius | Hubbs, 1924 | Tlaloc candalarius | Profundulidae | Headwater killifish |
| Profundulus chimalapensis | Del Moral-Flores, López-Segovia & Hernández-Arellano, 2020 | Genus Species | New species | |
| Profundulus guatemalensis | (Günther, 1866) | Profundulus guatemalensis | Profundulidae | |
| Profundulus hildebrandi | Miller, 1950 | Tlaloc hildebrandi | Profundulidae | Chiapas killifish |
| Profundulus kreiseri | Matamoros, Schaefer, Hernández & Chakrabarty, 2012 | Profundulus kreiseri | Profundulidae | Kreiser’s Killifish |
| Profundulus labialis | (Günther, 1866) | Tlaloc labialis | Profundulidae | Largelip killifish |
| Profundulus mexicanus | (Alvarez & Carranza, 1951) | Tlaloc labialis | Profundulidae | Largelip killifish |
| Profundulus mixtlanensis | Ornelas-García, Martínez-Ramírez & Doadrio, 2015 | Profundulus mixtlanensis | Profundulidae | |
| Profundulus mixtlanesis | Ornelas-García, Martínez-Ramírez & Doadrio, 2015 | Profundulus mixtlanensis | Profundulidae | |
| Profundulus oaxacae | (Meek, 1902) | Profundulus oaxacae | Profundulidae | |
| Profundulus pachycephalus | (Günther, 1866) | Profundulus punctatus | Profundulidae | Oaxaca killifish |
| Profundulus parentiae | Matamoros, Domínguez-Cisneros, Velázquez-Velázquez & McMahan, 2018 | Profundulus parentiae | Profundulidae | Parenti’s killifish |
| Profundulus portillorum | Matamoros & Schaefer, 2010 | Tlaloc portillorum | Profundulidae | |
| Profundulus punctatus | (Günther, 1866) | Profundulus punctatus | Profundulidae | Oaxaca killifish |
| Profundulus scapularis | Fowler, 1936 | Profundulus punctatus | Profundulidae | Oaxaca killifish |